American Conquest's basic gameplay mechanics and economic factors are shared with the earlier GSC Game World title Cossacks: European Wars and its add-ons. As in 'Cossacks', American Conquest allows the building of a base with which the player will conduct military and economic activities to prepare for victory in a scenario.

The campaign mode covers most of the major European powers' conquest in North America which includes the Spanish, the English and the French as well as the counter-campaigns narrated from the viewpoint of the native American Indians who fought against them.

Source: Wikipedia, "American Conquest", available under the CC-BY-SA License.